Table I.
Association between miR-518b expression and clinicopathological characteristics of patients with non-small cell lung cancer (n=118).
Serum miR-518b expression | Tissue miR-518b expression | ||||||
---|---|---|---|---|---|---|---|
Characteristic | Patients, n | Low (n=58) | High (n=60) | P-value | Low (n=54) | High (n=64) | P-value |
Age, years | 0.969 | 0.569 | |||||
≤60 | 47 | 23 | 24 | 20 | 27 | ||
>60 | 71 | 35 | 36 | 34 | 37 | ||
Sex | 0.879 | 0.265 | |||||
Female | 48 | 24 | 24 | 19 | 29 | ||
Male | 70 | 34 | 36 | 35 | 35 | ||
Smoking status | 0.732 | 0.554 | |||||
Never | 49 | 25 | 24 | 24 | 25 | ||
Previous/Current | 69 | 33 | 36 | 30 | 39 | ||
Histological type | 0.791 | 0.946 | |||||
Adenocarcinoma | 70 | 34 | 36 | 32 | 38 | ||
Squamous cell carcinoma | 36 | 19 | 17 | 16 | 20 | ||
Othersa | 12 | 5 | 7 | 6 | 6 | ||
Tumor size, cm | 0.042 | 0.014 | |||||
≤3 | 62 | 36 | 26 | 35 | 27 | ||
>3 | 56 | 22 | 34 | 19 | 37 | ||
Differentiation | 0.127 | 0.097 | |||||
Well/Moderate | 69 | 38 | 31 | 36 | 33 | ||
Poor | 49 | 20 | 29 | 18 | 31 | ||
TNM stage | 0.006 | 0.006 | |||||
I–II | 58 | 36 | 22 | 34 | 24 | ||
III–IV | 60 | 22 | 38 | 20 | 40 | ||
Lymph node metastasis | 0.039 | 0.031 | |||||
Negative | 66 | 38 | 28 | 36 | 30 | ||
Positive | 52 | 20 | 32 | 18 | 34 |
large cell carcinoma and adenosquamous carcinoma. miR, microRNA; TNM, tumor-node-metastasis.