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Mechanism of action of anlotinib. FGFR, fibroblast growth factor receptor; GDNF, glial cell line-derived neurotrophic factor; MAPK, mitogen-activated protein kinase; PDGFR, platelet-derived growth factor receptor; PLCγ, phospholipase γ 1; PKC, protein kinase C; RAS, rat sarcoma protein; SCF, stem-cell factor; VEGFR, vascular endothelial growth factor receptor; P, phosphate.
