Table 4.

The HSV-1/2 tissue tropism and the TRFs expression in different tissues

H high-expression, M middle expression, L little expression, N no-expression; The result from: http://biogps.org. Grading was based on fold increases compared to median fluorescence intensity on Affymetrix microarray chips at 0–2.5 (L), > 2.5- < 5 (M), > 5 (H)

System	Cell/ tissue	HSV-1	HSV-2	c-Rel	HNF-4	Elk-1	Pax-4	CF2-II	OCT-1
Blood system	CD34+ stem cell	+	_	H	H	H	H	H	H
	721 B lymphoblasts	+	_	H	H	H	H	M	H
	CD19 + B cell	+	_	H	H	H	H	M	H
	Leukemia lymphoblastic	+	_	M	M	M	M	L	L
	Bonemarrow	+	_	H	M	H	H	M	H
	Pituitariy	+	_	H	H	H	H	H	M
Head	Prefrontal Cortex	+	_	H	H	H	H	H	H
	Pineal	+	_	H	H	H	H	H	M
	Tongue	+	_	H	M	H	H	L	M
	Tonsil	+	_	H	M	M	H	L	L
	Retina	+	_	H	H	H	H	H	M
	Trigeminal ganglion	+	_	M	H	H	H	L	L
	Cerebellum	+	_	H	H	M	H	H	M
Viscera	Heart	+	_	H	H	H	H	H	M
	Lung	+	_	H	H	H	H	H	M
	Liver	+	_	H	H	H	H	H	M
	Kidney	+	_	M	M	M	M	H	L
	Smooth Muscles	+	_	H	H	H	H	H	M
	Adipocyte	+	_	H	M	M	H	L	L
Secretory system	Adrenalgland	+	_	M	M	H	H	L	L
	Pancreaticlstet	+	_	H	H	H	H	H	M
Genital system	Placenta	+	+	H	H	H	M	H	M
	Fetalthyroid	+	+	H	M	M	M	H	M
	Uterus	+	+	M	M	M	M	M	L
	Testis	+	+	M	M	M	M	H	L
	Ovary	+	+	M	M	L	L	L	M