Table 2. Effects of the SJE^a (200 mg/kg Bodyweight (BW)) on Growth Parameters, Tissue Index, and Serum Parameters in Diabetic KK-A^y Mice.

parameters	C57BL/6 + waterb	KK-Ay + waterc	KK-Ay + SJEc
Bodyweight (g)
0 week	22.24 ± 0.72	36.89 ± 0.68	37.05 ± 0.61
1 week	25.04 ± 0.86	39.57 ± 0.75	38.75 ± 0.47
2 week	25.78 ± 0.81	41.76 ± 1.05	38.77 ± 0.53*
3 week	26.24 ± 1.05	43.57 ± 1.05	39.41 ± 0.77**
4 week	26.88 ± 1.04	45.75 ± 1.19	40.73 ± 0.53**
5 week	24.32 ± 0.77	46.76 ± 1.56	41.82 ± 0.65*
food intake (g per day)	2.99 ± 0.09	5.29 ± 0.05	5.01 ± 0.08
Tissue Index (%)d
liver	3.79 ± 0.24	5.11 ± 0.29	3.88 ± 0.18*
epididymal WATe	1.00 ± 0.19	2.63 ± 0.13	2.44 ± 0.09
perirenal WAT	0.19 ± 0.07	1.29 ± 0.11	1.08 ± 0.07
BATf	0.31 ± 0.05	0.63 ± 0.07	0.87 ± 0.15
heart	0.53 ± 0.06	0.34 ± 0.01	0.37 ± 0.01
kidney	1.13 ± 0.09	0.99 ± 0.03	1.00 ± 0.02
Serum Lipids
TCg (mmol/L)	2.13 ± 0.24	3.77 ± 0.32	2.70 ± 0.13*
TGh (mmol/L)	0.64 ± 0.06	0.74 ± 0.02	0.60 ± 0.02*
HDL-ci (mmol/L)	2.18 ± 0.16	1.72 ± 0.19	2.34 ± 0.11*
LDL-cj (mmol/L)	0.05 ± 0.02	0.53 ± 0.11	0.19 ± 0.04*
Liver Function
ALTk (U/L)	27.5 ± 1.06	66.71 ± 10.79	38.25 ± 3.75*
ASTl (U/L)	112.5 ± 7.85	138.86 ± 9.96	122.75 ± 8.34
AST/ALT	4.11 ± 0.31	2.28 ± 0.16	3.36 ± 0.28**

^aSJE: Shui Jing fruit extract.

^bC57BL/6 mice as nondiabetic control (n = 10).

^cKK-A^y mice as a diabetic model (n = 10 for each group).

^dTissue index (%) = tissue weight (g)/bodyweight (g) × 100.

^eWAT: White adipose tissue.

^fBAT: Brown adipose tissue.

^gTC: Total cholesterol.

^hTG: Triglycerides.

ⁱHDL-c: High-density lipoprotein cholesterol.

^jLDL-c: Low-density lipoprotein cholesterol.

^kALT: Alanine aminotransferase.

^lAST: Aspartate transaminase. Values are expressed as the mean ± standard error (SE). *p < 0.05, **p < 0.01, compared to the KK-A^y + water group.