Table 2. Characteristics associated with overall Covid-19 illness severity^* in the total sample (N = 442).

	Age- and Sex-Adjusted Models		Multivariable-Adjusted Model†
	OR (95% CI)	P value	OR (95% CI)	P value
Age, per 10 years	1.68 (1.52,1.87)	<0.001	1.49 (1.30,1.70)	<0.001
Male sex	1.87 (1.26,2.77)	0.002	2.01 (1.34,3.04)	0.001
African American race∫	2.46 (1.45,4.18)	<0.001	2.13 (1.19,3.83)	0.011
Hispanic ethnicity	1.54 (0.91,2.60)	0.11	1.39 (0.79,2.45)	0.26
Obesity	1.96 (1.19,3.24)	0.009	1.95 (1.11,3.42)	0.021
Hypertension	1.97 (1.27,3.05)	0.003	1.19 (0.71,1.99)	0.52
Diabetes mellitus	2.25 (1.41,3.57)	0.001	1.77 (1.03,3.03)	0.037
Elixhauser comorbidity score, per SD	1.63 (1.33,2.01)	<0.001	1.77 (1.37,2.28)	<0.001
Prior myocardial infarction or heart failure	1.72 (0.96,3.09)	0.07	0.56 (0.27,1.18)	0.13
Prior COPD or asthma	1.23 (0.75,2.03)	0.41	0.76 (0.44,1.31)	0.34
ACE inhibitor use	0.69 (0.35,1.38)	0.29	0.48 (0.22,1.04)	0.06
Angiotensin receptor blocker use	1.18 (0.63,2.19)	0.61	1.05 (0.54,2.06)	0.89

*The primary outcome of Covid-19 illness severity score in the total sample was defined as an ordinal variable wherein: 0 = referent, 1 = required admission but never ICU level care, 2 = required ICU level care but never intubated, 3 = required intubation.

^† All listed covariates shown were included in the full multivariable-adjusted model.

^∫The referent is non-African American race.