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. 2020 Jul 23;15(7):e0236159. doi: 10.1371/journal.pone.0236159

Fig 7. CPL302-253 is bocks eosinophil infiltration to the lungs and IL-33 expression in HDM induced asthma mouse model.

Fig 7

Balb/c mice were immunized by s.c. route with CFA mixed with HDM lyophilized extract or saline. On day 12, 13 and 14 the mice were administrated by i.n. route with CPL302-253 or saline. On day 14, 60 min after compound administration the animals were challenged by i.n. route with HDM in sterile saline or saline. On day 15 eosinophils number (A) and IL-33 concentration (B) were measured in BAL.