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. 2020 Jul 23;15(7):e0236496. doi: 10.1371/journal.pone.0236496

Table 3. Inter-rater reliability and diagnostic agreement between an in-house LAMP test and AFB stain-fluorescence stain.

LAMP Test AFB Stain & Fluorescence stain
Positive Negative Total
Positive 40 4 44
Negative 4 59 63
Total 44 63 107
Agreement (%) 92.5%
Kappa (95%CI, p-value) 0.85 (0.74–0.95, p<0.001)
Spearman’s rho (p-value) 0.85 (p<0.001) *

Abbreviations: LAMP, loop-mediated isothermal amplification; CI, confidence interval.

*95% confidence interval of Spearman’s rank correlation is not estimable.