Table 2.
BMI <22 (
n = 478)
|
22–24.9 (
n = 1561)
|
25–29.9 (n = 5044) |
30–34.9 (n = 3600) |
35–39.9 (n = 1300) |
≥40 (n = 538) |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Outcomes | n | % | n | % | n | % | n | % | n | % | n | % | P-value |
All-cause mortality | 107 | 22.4 | 289 | 18.5 | 763 | 15.1 | 507 | 14.1 | 175 | 13.5 | 69 | 12.8 | <0.0001 |
CV mortality | 69 | 14.4 | 181 | 11.6 | 467 | 9.3 | 303 | 8.4 | 93 | 7.2 | 40 | 7.4 | 0.0004 |
Primary composite endpointa | 100 | 20.9 | 304 | 19.5 | 867 | 17.2 | 528 | 14.7 | 184 | 14.2 | 67 | 12.5 | 0.0024 |
Expanded composite endpointb | 129 | 27.0 | 463 | 29.7 | 1468 | 29.1 | 1007 | 28.0 | 334 | 25.7 | 113 | 21.0 | 0.7444 |
Non-fatal MI | 27 | 5.6 | 77 | 4.9 | 253 | 5.0 | 164 | 4.6 | 64 | 4.9 | 16 | 3.0 | 0.5437 |
Non-fatal Stroke | 20 | 4.2 | 86 | 5.5 | 243 | 4.8 | 129 | 3.6 | 42 | 3.2 | 16 | 3.0 | 0.0608 |
Total MI | 30 | 6.3 | 84 | 5.4 | 283 | 5.6 | 176 | 4.9 | 71 | 5.5 | 17 | 3.2 | 0.3661 |
Total stroke | 27 | 5.6 | 101 | 6.5 | 292 | 5.8 | 157 | 4.4 | 54 | 4.2 | 18 | 3.3 | 0.0618 |
Revascularization | 43 | 9.0 | 198 | 12.7 | 777 | 15.4 | 555 | 15.4 | 153 | 11.8 | 40 | 7.4 | 0.0005 |
HF hospitalization | 20 | 4.2 | 75 | 4.8 | 232 | 4.6 | 215 | 6.0 | 74 | 5.7 | 36 | 6.7 | <0.0001 |
P-values for differences between BMI groups, adjusted Cox regression model (type 3).
Primary composite endpoint: composite of first occurrence of cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke.
Expanded composite endpoint: composite of first occurrence of these three outcomes or revascularization or heart failure hospitalization.