Fig. 1.

Schematic overview of mitochondrion-organelle interactions and their physiological relevance. DGAT2, Diacylglycerol O-acyltransferase 2; DMT1, Divalent Metal Transporter 1; ER, Endoplasmic Reticulum; GRP75, Glucose-Regulated Protein 75; IPR3, 1,4,5–triphosphate receptor; LD, Lipid Droplet; LYS, Lysosome; MAVS, Mitochondrial Antiviral-signalling protein; MIGA2, Mitoguardin 2 protein; MITO, Mitochondrion; NLRP3, Nucleotide-binding oligomerization domain-like receptor protein 3; PLIN5, Perilipin-5 protein; PTPIP51, Protein Tyrosine Phosphatase Interacting Protein 51; STARD3, Star-related lipid transfer protein 3; VAPB, Vesicle-Associated Membrane Protein (VAMP)-associated Protein B; VDAC, Voltage-Dependent Anion-selective Channel; VPS13A, Vacuole Protein Sorting-associated protein 13 isoform A.