Table 2.

Observational case series involving Clinical and laboratory characteristics, Outcomes in TTS with covid-19 patients.

Author	Country and Sample (N)	Age (N) Median (IQR)	Comorbidities	Clinical Features and Medical Illness during Hospitalization	Ejection Fraction % median (IQR)	ECG changes	Cardiac Imaging	Troponin I ng/L median (IQR)	Improvement or Outcome	Management
Giustino G	USA N:5	57 (39–65)/M	Not Reported	4: Dyspnea 1: Chest pain (Acute Ischemic Stroke) 4: ARDS 4: AKI	36 (35–37)	2: ST Segment Elevation 1: Afib. with Rapid Ventricular response 1: Diffuse T wave Inversion 1: Sinus Tachycardia	4: Regional wall abnormalities typical of TTC including circumferential hypokinesis or akinesis of the apical and mid wall segments 1: patient had circumferential hypokinesis of the basal walls (consistent with reversed TTS).	11,400 (550–12,550)	2: Resolution of motion wall abnormalities on repeat TTE & discharged 1: Clinically improved & discharged 1: died on Mechanical Ventilation 1: died on VV ECMO	Not Reported

Abbreviations: IQR Interquartile range, VV ECMO veno-venous extracorporeal membrane oxygenation, TTE: Trans-thoracic echocardiography, ARDS: Acute respiratory distress syndrome, AKI: Acute kidney injury, Afib: Atrial fibrillation, TTS: Takotsubo Syndrome, M: Male.