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. 2020 Jul 11;12(13):12504–12516. doi: 10.18632/aging.103631

Table 1. Baseline characteristics, treatments, complications of patients infected with COVID-1.

Total (n=210) Discharged group (n=175) Deceased group (n=35) P Valuea
Age, median (IQR), y 71 (67-77) 70 (67-74) 74 (70-82) <0.001
Sex, n (%)
Male 101 (48) 79 (45) 22 (63) 0.056
Female 109 (52) 96 (55) 13 (37)
Duration from onset of symptoms to admission, median (IQR), d 10 (7-15) 10 (7-15) 8 (6-14) 0.889
Duration from admission to outcome, median (IQR), d 14 (10-17) 14 (11-17) 9 (5-15) <0.001
Duration from onset of symptoms to outcome, median (IQR), d 23 (17-28) 26 (21-29) 14 (12-24) <0.001
ICU cases, n (%) 18/198 (9) 2/167 (1) 16/31 (52) <0.001
Comorbidities, n (%) 159 (76) 124 (71) 35 (100) <0.001
Hypertension 115 (55) 97 (55) 18 (51) 0.664
Diabetes 38 (18) 29 (17) 9 (26) 0.200
Cardiovascular disease 52 (25) 35 (20) 17 (49) <0.001
COPD 3 (1) 2 (1) 1 (3) 0.435
Respiratory disease 38 (18) 20 (11) 18 (51) <0.001
Cerebrovascular disease 13 (6) 6 (3) 7 (20) <0.001
Chronic liver disease 18 (9) 12 (7) 6 (17) 0.047
Digestive diseases 21 (10) 15 (9) 6 (17) 0.123
Chronic kidney disease 18 (9) 8 (5) 10 (29) <0.001
Malignancy 6 (3) 3 (2) 3 (9) 0.026
Number of Comorbidities, n (%)
None 51 (24) 51 (29) 0 (0) <0.001
One 56 (27) 48 (27) 8 (23)
Two 60 (29) 54 (31) 6 (17)
Three 22 (10) 16 (9) 6 (17)
Four 13 (6) 4 (2) 9 (26)
Five 4 (2) 1 (1) 3 (9)
Six or more 4 (2) 1 (1) 3 (9)
Signs and symptoms, n (%)
Fever 151 (72) 122 (70) 29 (83) 0.115
Cough 148 (71) 118 (67) 30 (87) 0.031
Headache 13 (6) 10 (6) 3 (9) 0.523
Pharyngalgia 20 (10) 18 (10) 2 (6) 0.400
Fatigue 73 (35) 64 (37) 9 (26) 0.219
Anorexia 23 (11) 19 (11) 4 (11) 0.921
Nausea or vomiting 11 (5) 9 (5) 2 (6) 0.890
Myalgia 12 (6) 11 (6) 1 (3) 0.426
Chest stuffiness 76(36) 65(37) 11 (31) 0.522
Dyspnea 17 (8) 12 (7) 5 (14) 0.142
Diarrhea 24 (11) 21 (12) 3 (9) 0.562
First symptom, n (%)
Fever 107 (51) 88 (50) 19 (54) <0.001
Cough 65 (31) 55 (31) 10 (28)
Pharyngalgia 16 (8) 14 (8) 2 (6)
Fatigue 9 (4) 9 (5) 0 (0)
Anorexia 1 (0.5) 1 (0.5) 0 (0)
Chest tightness 6 (3) 4 (3) 2 (6)
Dyspnea 1 (0.5) 1 (0.5) 0 (0)
Diarrhea 5 (2) 3 (2) 2 (6)
Temperature, °C 36.8 (36.5-37.0) 36.7 (36.5-36.9) 37.0 (36.5-37.8) 0.069
Heart rate, median (IQR), beat per minute 80 (78-88) 80 (78-86) 85 (80-104) 0.016
Respiratory rate, median (IQR), beat per minute 20 (20-22) 20 (20-22) 22 (20-26) 0.008
Mean arterial pressure, median (IQR), mm Hg 97 (92-105) 97 (93-104) 100 (92-109) 0.585
Treatment, n (%)
Antiviral therapy 179/198 (90) 148/167 *(89) 31/31* (100) 0.048
Antibiotic therapy 163/198 (82) 133/167 (80) 30/31 (97) 0.022
Glucocorticoid therapy 65/198 (33) 42/167 (25) 23/31 (74) <0.001
Gamma globulin therapy 37/198 (19) 23/167 (14) 14/31 (45) <0.001
Albumin therapy 22/198 (11) 10/167 (6) 12/31 (39) <0.001
Oxygen inhalation 133/198 (67) 103/167 (62) 30/31 (97) <0.001
Mechanical ventilation 21/198 (11) 1/167 (1) 20/31 (66) <0.001
CRRT 3/198 (2) 1/167 (1) 2/31 (7) 0.014
Complications, n (%)
ARDS 27 (13) 2 (1) 25 (71) <0.001
Acute renal failure 4 (2) 0 (0) 4 (11) <0.001
Cerebral infarction 3 (1) 0 (0) 3 (9) <0.001

Abbreviations: COVID-19, coronavirus disease 2019; IQR, interquartile range; ICU, intensive care unit; COPD, chronic obstructive pulmonary diseases; CRRT, continuous renal replacement therapy; ARDS, acute respiratory distress syndrome. a P values indicate differences between the discharged group and the deceased group. P < 0.05 was considered statistically significant. *Record/data were missing in 8 patients in the discharged group, and in 4 patients in the deceased group regarding whether or not the patients received a treatment.