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. 2020 Jul 11;12(13):12504–12516. doi: 10.18632/aging.103631

Table 2. Laboratory findings of patients infected with COVID-19.

Laboratory finding within 24 hours on admission normal range Median (IQR) P valuea
Total (n=210) Discharged group (n=175) Deceased group (n=35)
Leucocytes, ×109/L, n (%) (3.5-9.5) ×109/L 5.2 (3.9-6.4) 5.1 (3.9-6.1) 6.4 (4.1-10.7) 0.037
<3.5 ×109/L 30 (14) 24 (14) 6 (17) <0.001
3.5-9.5 ×109/L 168 (80) 148 (84) 20 (57)
≥9.5 12 (6) 3 (2) 9 (26)
C-reactive protein, mg/L, n (%) (0-5) mg/L 15.5 (3.2-63.6) 9.3 (2.6-37.2) 125.8 (49.1-200.0) <0.001
0-5 mg/L 68 (32) 68 (39) 0 (0) <0.001
≥5 mg/L 142 (68) 107 (61) 35 (100)
Lymphocyte, ×109/L, n (%) (1.1-3.2) ×109/L 1.1 (0.8-1.5) 1.1 (0.9-1.6) 0.7 (0.4-0.9) <0.001
<0.8 ×109/L 52 (25) 31 (18) 21 (60) <0.001
0.8-1.1 ×109/L 42 (20) 35 (20) 7 (20)
1.1-3.2×109/L 114 (54) 107 (61) 7 (20)
≥3.2×109/L 2 (1) 2 (1) 0 (0)
Neutrophils, ×109/L, n (%) (1.8-6.3) ×109/L 3.3 (2.4-4.5) 3.0 (2.4-4.3) 5.2 (2.7-10.0) 0.003
<1.8 ×109/L 20 (10) 16 (9) 4 (11) <0.001
1.8-6.3 ×109/L 165 (78) 149 (85) 16 (46)
≥6.3 ×109/L 25 (12) 10 (6) 15 (43)
NLR 2.9 (1.9-5.1) 2.8 (1.8-3.8) 8.4 (3.1-13.1) <0.001
Monocytes, ×109/L (0.1-0.6) ×109/L 0.4 (0.3-0.5) 0.4 (0.3-0.5) 0.4 (0.2-0.5) 0.225
Procalcitonin, ng/mL, n (%) (0.02-0.05) ng/mL
<0.02 ng/mL 0 0 0 <0.001
0.02-0.05 ng/mL 140/205 (68) 135/170 (79) 5 (14)
≥0.05 ng/mL 65/205 (32) 35/170 (21) 30 (86)
Platelet count, ×109/L, n (%) (125-350) ×109/L 206.0 (159.8-267.0) 216.0 (169.0-285.0) 168.0 (124.0-216.0) <0.001
<125 ×109/L 20/208 (10) 19/174 (11) 1/34 (3) 0.010
125-350 ×109/L 164/208 (79) 139/174 (80) 25/34 (74)
≥350 ×109/L 24/208 (11) 16/174 (9) 8/34 (23)
ALT, IU/L, n (%) (7-40) IU/L 29.5 (17.0-45.5) 27.0 (17.0-43.0) 35.0 (18.0-77.0) 0.427
<7 IU/L 1/208 (0.5) 0/173 (0) 1 (3) 0.261
7-40 IU/L 140/208 (67) 121/173 (70) 19 (54)
≥40 IU/L 67/208 (32.5) 52/173 (30) 15 (43)
AST, IU/L, n (%) (0-45) IU/L 26.0 (21.0-38.3) 25.0 (20.0-35.5) 45.0 (26.0-72.0) 0.008
<45 IU/L 165/208 (79) 149/173 (86) 16 (46) <0.001
≥45 IU/L 43/208 (21) 24/173 (14) 19 (54)
Cr, μmol/L, n (%) (40-105) μmol/L 67.1 (56.5-84.1) 65.2 (55.2-80.2) 76.0 (64.0-107.4) 0.012
<40 μmol/L 2/208 (1) 1/173 (0.5) 1 (3) 0.139
40-105μmol/L 197/208 (95) 167/173 (96.5) 30 (86)
≥105μmol/L 9/208 (4) 5/173 (3) 4 (11)
BUN, mmol/L, n (%) (3.1-7.2) mmol/L 4.7 (3.4-6.1) 4.4 (3.3-5.6) 7.2 (5.0-11.1) <0.001
<3.1 mmol/L 28 (13) 26 (15) 2 (5) <0.001
3.1-7.2 mmol/L 146 (70) 130 (74) 16 (46)
≥7.2 mmol/L 36 (17) 19 (11) 17 (49)
CK, IU/L, n (%) (30-180) IU/L 65.0 (43.0-116.0) 60.0 (41.0-91.5) 137.0 (54.0-363.0) 0.008
<30 IU/L 19/208 (9) 16/173 (9) 3 (9) <0.001
30-180 IU/L 162/208 (78) 144/173 (83) 18 (51)
≥180 IU/L 27/208 (13) 13/173 (8) 14 (40)
CK-MB, IU/L, n (%) (0-25) IU/L 10.0 (7.0-13.0) 9.0 (7.0-12.0) 13.0 (8.0-19.0) 0.002
<25 IU/L 204/208 (98) 171/173 (99) 33 (94) 0.074
≥25 IU/L 4/208 (2) 2/173 (1) 2 (6)
APTT, s (21-35) s 27.6 (23.7-31.4) 27.3 (23.5-30.6) 31.3 (26.0-35.4) 0.012
Prothrombin time, s (10-13) s 11.6 (11.0-12.4) 11.6 (10.9-12.3) 12.1 (11.5-12.8) 0.035
Thrombin time, s (13-21) s 19.5 (16.4-22.2) 19.6 (14.9-22.3) 18.7 (17.4-21.4) 0.180
D-dimer, μg/mL, n (%) (<0.5) μg/mL 0.6 (0.2-1.9) 0.6 (0.2-1.1) 3.6 (0.6-5.7) <0.001
0-0.5 μg/mL 42/168 (25) 40/139 (29) 2/29 (7) 0.014
≥0.5 μg/mL 126/168 (75) 99/139 (71) 27/29 (93)
Albumin, g/L, n (%) (40-55) g/L 35.7 (31.9-39.3) 36.2 (32.8-39.6) 31.2 (26.7-34.6) <0.001
<30 g/L 30/206 (15) 17/172 (10) 13/34 (38) <0.001
Glucose, mmol/L, n (%) (3.9-6.1) mmol/L 5.7 (4.7-7.4) 5.5 (4.7-6.9) 6.9 (5.0-7.9) 0.105
<3.9 mmol/L 2/205 (1) 2/171 (1) 0/34 (0) <0.001
3.9-6.1 mmol/L 123/205 (60) 112/171 (66) 11/34 (32)
≥6.1 mmol/L 80/205 (39) 57/171 (33) 23/34 (68)
Total bilirubin, μmol/L (2-21) μmol/L 8.9 (6.6-11.9) 8.4 (6.5-11.6) 9.6 (6.7-16.7) 0.043
Triglyceride, mmol/L (0.5-1.72) mmol/L 1.2 (0.9-1.7) 1.2 (0.9-1.6) 1.3 (0.9-1.9) 0.635
Total cholesterol, mmol/L (3.1-5.7) mmol/L 3.9 (3.3-4.6) 4.0 (3.5-4.6) 3.4 (2.8-4.2) 0.051
Lactate dehydrogenase, IU/L, n (%) (114-240) IU/L 208.0 (165.8-270.8) 199.0 (164.0-244.0) 367.0 (251.0-547.0) <0.001
<240 IU/L 128/205 (62) 121/171 (71) 7/34 (21) <0.001
≥240 IU/L 77/205 (38) 50/171 (29) 27/34 (79)

Abbreviations: COVID-19, coronavirus disease 2019; IQR, interquartile range; NLR, neutrophil-to-lymphocyte ratio; ALT, alanine aminotransferase; AST, aspartate aminotransferase; Cr, serum creatinine; BUN, blood urea nitrogen; CK, creatine kinase; CK-MB, creatine kinase isoenzyme; APTT, activated partial thromboplastin time. a P values indicate differences between the discharged group and the deceased group. P < 0.05 was considered statistically significant.