Table 3. Quantitative data synthesis for the associations of age with severity and prognosis of COVID-19.

Variables	No of studies	Total cases	P heterogeneity	I2 (%)	SMD (95% CIs)	P value	P Egger
Severity	32	8140	<0.001	92.4	0.73 (0.53-0.94)	<0.001	0.331
Death	9	3725	0.005	63.9	1.06 (0.85-1.26)	<0.001	0.610
Admission to ICU	5	2224	0.189	34.9	0.78 (0.60-0.96)	<0.001	0.538
Composite endpoint	2	2879	0.055	72.9	0.88 (0.56-1.21)	<0.001	-
ARDS	3	2090	0.939	0	0.83 (0.67-0.99)	<0.001	0.882
Invasive ventilation	2	1825	0.493	0.0	0.84 (0.54-1.14)	<0.001	-
Cardiac abnormality	4	439	0.041	63.6	0.92 (0.44-1.41)	<0.001	0.885
Disease progression	2	219	<0.001	95.4	2.37 (0.00-4.74)	0.050	-