Table 4. Multivariate linear model results for association between miRNA-29s and cognitive domain z-scores of patients with Parkinson’s disease.
Cognitive domain z-score | miRNA-29a | miRNA-29b | miRNA-29c | |
β=1.104 | β=1.240 | β=1.391 | ||
Global | 95% CI=--0.025 to 2.233 | 95% CI=0.154 to 2.327 | 95% CI=0.238 to 2.545 | |
p=0.055 | p=0.026* | p=0.019* | ||
β=0.181 | β=0.198 | β=0.257 | ||
Attention | 95% CI=-0.092 to 0.454 | 95% CI=-0.053 to 0.449 | 95% CI=-0.019 to 0.532 | |
p=0.191 | p0.121 | p=0.068 | ||
β=0.132 | β=0.309 | β=0.146 | ||
Executive | 95% CI=-0.142 to 0.405 | 95% CI=0.060 to 0.559 | 95% CI=-0.140 to 0.432 | |
p=0.341 | p=0.016* | p=0.312 | ||
β=0.354 | β=0.339 | β=0.247 | ||
Language | 95% CI=0.039 to0.669 | 95% CI=0.033 to 0.645 | 95% CI=-0.083 to 0.577 | |
p=0.028* | p=0.030* | p=0.140 | ||
β=0.455 | β=0.453 | β=0.483 | ||
Memory | 95% CI=0.090 to 0.821 | 95% CI=0.096 to 0.811 | 95% CI=0.102 to 0.864 | |
p=0.015* | p=0.014* | p=0.014* | ||
β=0.350 | β=0.284 | β=0.157 | ||
Visuospatial | 95% CI=-0.198 to 0.898 | 95% CI=-0.251 to 0.818 | 95% CI=-0.417 to 0.730 | |
p=0.207 | p=0.294 | p=0.588 |
Multivariate linear regression model, adjusted for years of education and UPDRS-III subscore.
Cognitive domain z-scores were derived from two or more neuropsychological test scores.
*, p<0.05