Table 5. Correlations between miRNA-29s and clinical characteristics of patients with Parkinson’s disease.
miRNA-29a## | miRNA-29b## | miRNA-29c | ||||
r | p value | r | p value | r | p value | |
Age, years | 0.117 | 0.251 | 0.122 | 0.233 | 0.114 | 0.262 |
Gender## | -0.059 | 0.567 | -0.084 | 0.411 | -0.008 | 0.940 |
Education, years | 0.000 | 0.998 | -0.003 | 0.975 | -0.031 | 0.768 |
Disease duration, months## | 0.047 | 0.664 | -0.113 | 0.292 | 0.049 | 0.648 |
UPDRS-III subscore | -0.097 | 0.350 | -0.087 | 0.403 | 0.024 | 0.817 |
Hoehn and Yahr stage## | -0.029 | 0.776 | -0.023 | 0.828 | 0.111 | 0.280 |
ESS score## | 0.094 | 0.364 | 0.003 | 0.975 | 0.109 | 0.292 |
GDS score | -0.124 | 0.234 | -0070 | 0.502 | -0.039 | 0.707 |
SSST 12 score | -0.025 | 0.811 | 0.027 | 0.798 | -0.015 | 0.882 |
RBDSQ score | 0.058 | 0.587 | 0.031 | 0.768 | 0.077 | 0.468 |
Hallucination## | -0.098 | 0.338 | 0.016 | 0.878 | -0.080 | 0.437 |
LED (mg/day)## | -0.043 | 0.713 | -0.109 | 0.344 | 0.195 | 0.090 |
P values correspond to correlation between miRNA-29s and clinical characteristics.
Abbreviations: UPDRS, Unified Parkinson’s Disease Rating Scale. ESS, Epworth Sleepiness Scale. GDS, Geriatric Depression Scale. SSST 12, the Sniffin’ Sticks Screening 12 Test. RBDSQ, Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire. LED, Levodopa equivalent dose.
#Off-state motor ratings according to the UPDRS (motor section).
## P values correspond to spearman correlation test for unnormal-distributed data.