Table 2. Results of univariate and multivariate analyses of postoperative patients’ survival by Cox’s proportional hazard model.
Varieties | n | Univariate analysis | Multivariate analysis | ||||
HR | 95% CI | P | HR | 95% CI | P | ||
Age (≤60 or >60 years) | 57/78 | 1.084 | 0.696-1.687 | 0.722 | |||
Gender (Male / Female) | 77/58 | 0.876 | 0.561-1.366 | 0.559 | |||
Size of tumor (≤5 or >5 cm) | 59/76 | 0.654 | 0.418-1.023 | 0.063 | |||
Depth of tumor invasion (T1-2 / T3-4) | 25/110 | 0.223 | 0.102-0.487 | <0.001c | 0.360 | 0.161-0.805 | 0.013a |
Lymph node metastasis (negative / positive) | 66/69 | 0.179 | 0.108-0.298 | <0.001c | 7.731 | 1.656-36.084 | 0.009b |
Degree of differentiation (moderate-well/poor) | 111/24 | 0.461 | 0.270-0.787 | 0.005b | 0.799 | 0.457-1.395 | 0.429 |
TNM staging (I-II / III-IV) | 64/71 | 0.157 | 0.093-0.264 | <0.001c | 0.033 | 0.006-0.164 | <0.001c |
AKR1B10 expression (negative / positive) | 67/68 | 3.880 | 2.403-6.266 | <0.001c | 2.492 | 1.491-4.164 | <0.001c |
a P < 0.05, b P < 0.01, c P < 0.001