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. 2020 Jul 2;12(13):13059–13075. doi: 10.18632/aging.103393

Table 2. Results of univariate and multivariate analyses of postoperative patients’ survival by Cox’s proportional hazard model.

Varieties n Univariate analysis Multivariate analysis
HR 95% CI P HR 95% CI P
Age (≤60 or >60 years) 57/78 1.084 0.696-1.687 0.722
Gender (Male / Female) 77/58 0.876 0.561-1.366 0.559
Size of tumor (≤5 or >5 cm) 59/76 0.654 0.418-1.023 0.063
Depth of tumor invasion (T1-2 / T3-4) 25/110 0.223 0.102-0.487 <0.001c 0.360 0.161-0.805 0.013a
Lymph node metastasis (negative / positive) 66/69 0.179 0.108-0.298 <0.001c 7.731 1.656-36.084 0.009b
Degree of differentiation (moderate-well/poor) 111/24 0.461 0.270-0.787 0.005b 0.799 0.457-1.395 0.429
TNM staging (I-II / III-IV) 64/71 0.157 0.093-0.264 <0.001c 0.033 0.006-0.164 <0.001c
AKR1B10 expression (negative / positive) 67/68 3.880 2.403-6.266 <0.001c 2.492 1.491-4.164 <0.001c

a P < 0.05, b P < 0.01, c P < 0.001