Table 1. Sample demographics.
AD patients | CU subjects | |
N | 72 | 31 |
Females N (%) | 34 (47.2%) | 15 (48.4%) |
Age mean (sd) | 76 (7.4) | 74 (4.4) |
Age at disease onset median(mad) | 71 (8.9) | - |
Years of education median(mad) | 16 (3) | 16 (3) |
MMSE median(mad) | 24 (1.5) | 29 (0) |
CDR global score median(mad) | 0.72 (0.25) | 0 (0) |
ApoE e4 allele carrier N (%) | 50 (69.4%) | 3 (9.7%) |
CSF Aβ1-42, median(mad) | 137.38 (23.98) | 234.11 (20.88) |
CSF pTau 181, median(mad) | 37.5 (12.6) | 18 (4.45) |
ADAS word recall mean (sd) | 6.17 (1.43) | 2.81 (0.95) |
Mad: maximum median distance, MMSE: mini mental state examination, ADAS: Alzheimer’s Disease Assessment Scale, CDR: Clinical Dementia Rating, CSF: cerebrospinal fluid. CSF values are in pg/ml. CU: cognitively unimpaired.