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. 2020 Jun 30;12(13):12987–13004. doi: 10.18632/aging.103385

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Copyright © 2020 Wang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Over-represented target genes and transcription factors of the miRNAs showed consistent or reversed artery-versus-venous deregulation between young and aged rats. (A) Heatmap of genes intensively regulated by miRNAs showing reversed deregulation and their functional association. (B) Network view of the interactions between miRNAs showing consistent deregulation and their over-represented upstream transcription factors. (C) Network view of the interactions between miRNAs showing reversed deregulation and their over-represented upstream transcription factors.