Table 3. Metabolic pathways associated with top 6 age-related acylcarnitines by gender.

Metabolic Pathway	Number of metabolites at p < 0.05	Number of metabolites from pathway detected	p-value
Females
Cytochrome P450 drug metabolism	5	26	0.001
Glycerophospholipid metabolism	4	28	0.004
Leukotriene metabolism	6	51	0.004
Vit E metabolism	4	30	0.006
Fatty acid activation	3	24	0.017
Glycosphingolipid metabolism	3	25	0.020
Prostaglandin formation	4	40	0.028
Tryptophan metabolism	4	41	0.032
Fatty acid biosynthesis	3	29	0.039
Males
Vit E metabolism	6	30	0.001
Carnitine shuttle	5	28	0.002
Cholesterol biosynthesis	4	31	0.011
Steroid biosynthesis	5	53	0.030
Cytochrome P450 drug metabolism	3	25	0.030