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. 2020 Jul 4;12(13):12960–12986. doi: 10.18632/aging.103384

Table 3. hAMSCs high-secreted proteins positive biological phenomenon function in keratinocytes.

GO Terms ID GO Terms Level GO Terms Description Gene name
GO:0016331 7 morphogenesis of embryonic epithelium CTHRC1, RPS7
GO:0008284 6 positive regulation of cell proliferation NRP1, CTHRC1, HTRA1, MYDGF, PDGFD, GLUL, TIMP1, CYR61
GO:0030154 5 cell differentiation SPON2, NRP1, LOXL2, HTRA1, GPC1, SERPINF1, COL4A1, MMP14, SPOCK1, MATN2, MAP1B, COL3A1, COL4A2, EXT1, COL12A1, SERPINE2, CYR61, B4GAT1, CTHRC1, MYH9, LGALS1, INHBA, SERPINH1, RPS7, CDH2, POSTN, VCAN, GLO1, COL6A1
GO:0090132 5 epithelium migration NRP1, LOXL2, MYH9
GO:0050793 4 regulation of developmental process NRP1, LOXL2, GPC1, SERPINF1, MYDGF, COLQ, MMP14, SPOCK1, MAP1B, COL3A1, COL4A2, SERPINE2, CYR61, SRPX2, CTHRC1, MYH9, LGALS1, PDGFD, INHBA, EFEMP1, PPIB, C3, CDH2, POSTN, TIMP1, SERPINE1, DCN
GO:0042060 5 wound healing COL1A2, ANXA5, MYH9, MYL9, PDGFD, COL3A1, POSTN, TIMP1, PROCR, SERPINE2, CYR61, DCN
GO:0002009 6 morphogenesis of an epithelium NRP1, CTHRC1, COL4A1, MMP14, RPS7, CYR61
GO:0040017 5 positive regulation of locomotion CXCL3, SRPX2, NRP1, POSTN, SERPINE1, PDGFD, MMP14, CYR61
GO:0010632 8 regulation of epithelial cell migration SRPX2, NRP1, SERPINF1, DCN
GO:0045597 6 positive regulation of cell differentiation NRP1, CTHRC1, LOXL2, GPC1, SERPINF1, INHBA, MMP14, CDH2, MAP1B, SERPINE2, CYR61
GO:0090130 4 tissue migration NRP1, LOXL2, MYH9
GO:0060284 6 regulation of cell development NRP1, LGALS1, SERPINF1, SPOCK1, CDH2, MAP1B, COL3A1, POSTN, SERPINE2
GO:1903034 6 regulation of response to wounding SERPINE2
GO:0045595 5 regulation of cell differentiation NRP1, LOXL2, GPC1, SERPINF1, MMP14, SPOCK1, MAP1B, COL3A1, SERPINE2, CYR61, CTHRC1, LGALS1, INHBA, EFEMP1, CDH2, POSTN
GO:0030307 7 positive regulation of cell growth NRP1, MMP14, MAP1B
GO:0009611 4 response to wounding COL1A2, ANXA5, NRP1, MYH9, LGALS1, MYL9, PDGFD, MATN2, COL3A1, POSTN, TIMP1, PROCR, SERPINE2, CYR61, DCN
GO:0010631 8 epithelial cell migration NRP1, LOXL2, MYH9
GO:0048771 4 tissue remodeling CTHRC1, MMP14
GO:0009888 4 tissue development NRP1, LOXL2, COL4A1, MMP14, COL3A1, COL4A2, EXT1, COL12A1, SERPINE2, CYR61, CTHRC1, INHBA, SERPINH1, CDH2, RPS7, POSTN, PLOD1, TIMP1, COL6A1, DCN
GO:0040012 4 regulation of locomotion CXCL3, SRPX2, NRP1, SERPINF1, PDGFD, MMP14, COL3A1, POSTN, SERPINE1, TIMP1, SERPINE2, CYR61, DCN