TABLE 2.
Clinicopathological features of the patients and correlation with HIF‐2α protein
| Low expression | High expression | P‐value | Total | |
|---|---|---|---|---|
| Age‐year | ||||
| Median | 58 | 59 | .679 a | 58 |
| Range | 24‐82 | 27‐82 | 24‐82 | |
| Age‐year‐no. (%) | ||||
| ≤60 | 106 (59) | 86 (57) | .722 b | 192 (58) |
| >60 | 74 (41) | 65 (43) | 139 (42) | |
| Gender‐no. (%) | ||||
| Male | 127 (71) | 102 (68) | .555 b | 229 (69) |
| Female | 53 (29) | 49 (32) | 102 (31) | |
| Fuhrman Grade‐no. (%) | ||||
| I + II | 123 (68) | 83 (55) | .012 b | 206 (62) |
| III + IV | 57 (32) | 68 (45) | 125 (38) | |
| TNM stage‐no. (%) | ||||
| I + II | 143 (79) | 112 (74) | .256 b | 255 (77) |
| III + IV | 37 (21) | 39 (26) | 76 (23) | |
| pT stage‐no. (%) | ||||
| T1 + 2 | 148 (82) | 121 (80) | .627 b | 269 (81) |
| T3 + 4 | 32 (18) | 30 (20) | 62 (19) | |
| pN stage‐no. (%) | ||||
| N0 | 174 (97) | 141 (93) | .165 b | 315 (95) |
| N1 | 6 (3) | 10 (7) | 16 (5) | |
| pM stage‐no. (%) | ||||
| M0 | 156 (87) | 129 (85) | .746 b | 285 (86) |
| M1 | 24 (13) | 22 (15) | 46 (14) | |
| Tumour burden‐cm | ||||
| Median | 4 | 4.5 | .371 a | 4 |
| Range | 0.8‐11.3 | 0.8‐12 | 0.8‐12 | |
| Tumour burden‐cm‐no. (%) | ||||
| ≤4 | 101 (56) | 71 (47) | .099 b | 172 (52) |
| >4 | 79 (44) | 80 (53) | 159 (48) | |
a
Mann‐Whitney U test.
b
chi‐square test; TNM stage: AJCC renal cancer in 2010.