Figure 4.

Scatterplots of associations between Autism Diagnostic Observation Schedule (ADOS) total scores, connectivity with the left fusiform gyrus, and specific intrinsic connectivity networks (ICNs). Connectivity was measured by simple correlations (simple corrs.) between voxel and ICN time series. ADOS total scores were negatively associated with connectivity between the left fusiform gyrus and seven influential ICNs, including the medial and Left Sensorimotor networks (med SM and L SM, respectively), the ventral Default Mode Network (vDMN), and a Language network centered on the bilateral temporoparietal junction (Language-TPJ). Less influential negative associations between ADOS total scores were observed for connectivity between the left fusiform gyrus and the primary Visual network (prim Visual), and anterior Salience Networks centered on the dorsal Anterior Cingulate Cortex (aSN-dACC) and anterior insula (aSN-aIns). The x-axis plots correlations between all voxels included in cluster and each specific ICN, for each subject. The y-axis plots ADOS total scores for each subject. Inset in the top left shows anatomical cluster and connectivity corresponding to the left fusiform gyrus in Figure 2.