Table 1.

Top 20 of hub miRNAs in young and old obtained from CytoHubba analysis.

Hub miRNAs in young					Hub miRNAs in old
Rank	Name	Score MCC	logFC	adj.P.Val	Rank	Name	Score MCC	logFC	adj.P.Val
1	hsa-miR-31-5p	7716	− 2.021	0.00001	1	hsa-miR-32-5p	182	1.372	0.00007
2	hsa-miR-224-5p	7705	− 1.052	0.00000	2	hsa-miR-96-5p	169	1.216	0.00006
3	hsa-miR-3065-3p	744	− 1.082	0.00051	3	hsa-miR-182-3p	168	1.007	0.00942
4	hsa-miR-205-5p	6858	− 2.804	0.00002	4	hsa-miR-183-5p	160	0.986	0.00000
5	hsa-miR-205-3p	6738	− 2.283	0.00003	5	hsa-miR-375	156	1.297	0.00000
6	hsa-miR-3545-3p	6368	− 2.509	0.00000	6	hsa-miR-183-3p	126	0.886	0.00454
7	hsa-miR-224-3p	5544	− 1.052	0.00000	7	hsa-miR-224-3p	90	− 1.066	0.00039
8	hsa-miR-676-3p	5424	− 1.249	0.00024	8	hsa-miR-205-5p	80	− 2.327	0.00000
9	hsa-miR-135b-5p	1680	− 1.951	0.00161	9	hsa-miR-224-5p	72	− 1.142	0.00000
10	hsa-miR-452-3p	1560	− 0.761	0.00090	10	hsa-miR-31-5p	60	− 1.813	0.00018
11	hsa-miR-488-3p	846	− 1.368	0.00358	11	hsa-miR-3545-3p	48	− 1.829	0.00012
12	hsa-miR-1911-5p	762	− 2.578	0.00027	12	hsa-miR-452-5p	42	− 1.014	0.00000
13	hsa-miR-1912	732	− 2.022	0.00228	13	hsa-miR-32-3p	36	1.101	0.00160
14	hsa-miR-509–3-5p	258	− 2.235	0.00032	14	hsa-miR-1298	24	− 1.855	0.07505
15	hsa-miR-31-3p	246	− 1.557	0.00157	15	hsa-miR-10a-3p	24	− 0.391	0.29418
16	hsa-miR-452-5p	244	− 0.974	0.00000	16	hsa-miR-5096	24	1.181	0.00334
17	hsa-miR-150-5p	26	1.120	0.00005	17	hsa-miR-1911-5p	24	− 1.032	0.19284
18	hsa-miR-142-5p	26	1.140	0.00008	18	hsa-miR-1912	24	NS	NS
19	hsa-miR-146b-3p	25	1.568	0.00000	19	hsa-miR-205-3p	24	− 1.942	0.00006
20	hsa-miR-514a-3p	24	− 2.516	0.00008	20	hsa-miR-944	18	− 1.988	0.00000