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. 2020 Aug;10(8):1699–1722. doi: 10.21037/qims-19-1048

Table 5. Reference values in healthy people detected with US.

Parameter Reference Male Female
RF muscle thickness Minetto et al. (75), 2016 20 mm* 16 mm*
Mean age: 26±3 years
Delaney et al. (85), 2010 2.3±0.3 cm; mean age: 24.6±1.45 years N/A**
Ema et al. (78), 2013 20.7±3.9 mm; mean age: 24±1 years
Strasser et al. (76), 2013 18.1±4 mm; mean age: 24.2±3.7 years
RF CSA Seymour et al. (70), 2009 463±137 mm2; mean age: 63±9 years
Delaney et al. (85), 2010 8.8±2.1 cm2; mean age: 24.6±1.45 years N/A**
QMLT Tillquist et al. (71), 2014 2.01–2.09±0.50–0.52 cm; mean age: 30.6±8.4 years
Arts et al. (77), 2010 R: 4.16±1.02 cm; L: 4.07±0.97 cm; mean age: 47 years R: 3.64±0.76 cm; L: 3.57±0.72 cm; mean age: 48 years
PA Strasser et al. (76), 2013 RF***: –; musculus intermedius: 9.7°±2.6°; vastus lateralis: 14.7°±2.5°; vastus medialis: 12.1°±2°; mean age: 24.2±3.7 years
EI**** Strasser et al. (76), 2013 RF: 101.9±14; musculus intermedius: 77.7±20.1; vastus lateralis: 96.2±14.9; vastus medialis: 94.3±17.8; mean age: 24.2±3.7 years

*, Values 2 SDs below the sex-specific means of the sample of young subjects have been taken from the indicated reference (cut-off values used to detect low muscle mass in the indicated study). **, Female gender not included in the study. ***, The orientation of the fibers of the RF was almost parallel to their fascia, so no PA was determined. ****, EI assessed with ImageJ (National Institutes of Health, USA) software. RF, rectus femoris; CSA, cross-sectional area; QMLT, quadriceps muscle layer thickness; R, right. L, left; PA, pennation angle; EI, echo intensity.