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. 2020 May 27;75(3):396–403. doi: 10.1007/s11130-020-00826-y

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© The Author(s) 2020

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Fig. 5 — P-glycoprotein (P-gp) activity (intracellular accumulation of the P-gp substrate rhodamine 123) quantified in LS-180 cells incubated with 12.5–200 μmol/L CnAMP1 for 48 h. P-gp activity was determined in the presence (black bars) or absence (dashed bars) of the P-gp inhibitor Elacridar. Data represent mean ± SD of three independent experiments performed in triplicate. *Significantly different from control (one-way ANOVA) and significantly different from cells in the presence of Elacridar (two-way ANOVA) at p < 0.05