Table 3.
Comparison of septic versus non-septic burn patients.
| Variable | Septic (n = 92) | Non-septic (n = 119) | P-value |
|---|---|---|---|
| A. Demographics | |||
| Mean (SD) age (years) | 44.5 (18.1) | 38.6 (15.7) | NS |
| Mean (SD) TBSA (%) | 38.9 (16.9) | 21.7 (10.8) | 0.033 |
| Gender (M/F) | 59/33 | 80/39 | NS |
| Inhalation injury (%) | 14.1% | 13.9% | NS |
| ICU LOS (days) | 58.7 (25.6) | 40.2 (26.2) | 0.021 |
| Median (IQR) # infections per patient | |||
| Bloodstream | 5.5 (6.0) | N/A | N/A |
| Pneumonia | 7.2 (5.5) | N/A | N/A |
| Urinary tract | 3.6 (2.7) | N/A | N/A |
| Wound | 4.4 (3.6) | N/A | N/A |
| Mortality (%) | 31.5 | 11.8 | 0.001 |
| Mean GCS (SD) | 10.3 (2.8) | 11.4 (2.8) | 0.005 |
| Mean (SD) MODS | 4.4 (2.8) | 3.9 (2.7) | 0.006 |
| Mean (SD) SOFA | 4.1 (2.7) | 3.2 (2.3) | < 0.001 |
| B. Laboratory data | |||
| Median Temperature (IQR) (ºC) | 39.2 (4.0) | 38.0 (3.5) | 0.010 |
| Median HCT (IQR) (%) | 24.0 (7.0) | 25.5 (8.6) | 0.003 |
| Median HGB (IQR) (g/dL) | 7.8 (2.2) | 8.5 (3.0) | < 0.001 |
| Median WBC (IQR) (cells/µL) | 13.1 (10.7) | 12.1 (9.0) | 0.001 |
| Median creatinine (IQR) (mg/dL) | 0.80 (0.91) | 0.71 (0.38) | < 0.001 |
| Median BUN (IQR) (mg/dL) | 21 (20.8) | 13 (9.8) | < 0.001 |
| Mean Na+ (SD) (mmol/L) | 139.2 (5.28) | 136.8 (4.53) | < 0.001 |
| Mean TCO2 (SD) (mmol/L) | 26.8 (4.9) | 24.8 (3.68) | 0.001 |
| Median PLT (IQR) (cells/µL) | 289 (300.5) | 352.5 (344.8) | < 0.001 |
BUN blood urea nitrogen, HCT hematocrit, HGB hemoglobin, ICU intensive care unit, F female, GCS Glascow Coma Score, IQR interquartile range, LOS length-of-stay, M male, MODS multiple organ dysfunction score, N/A not applicable, Na+ ionized sodium, NS not significant, PLT platelet count, SD standard deviation, SOFA sequential organ failure assessment score, TBSA total body surface area, TCO2 total CO2, and WBC white blood cell count.