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. 2020 Jul 23;10:12380. doi: 10.1038/s41598-020-69403-2

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© The Author(s) 2020, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The effect of RB on cell viability. (A) The MTT assay performed for observing the effect of various concentrations of RB on cell viability. RB showed minimal cytotoxicity up to 500 irradiation. (B) The PE-RB showed negligible cytotoxicity at a concentration of 500 nM. Whereas, the cells treated with 2.5 µM Tau aggregates also showed very minimal reduction in cell viability. p < 0.05, **p < 0.001, ***p < 0.0001 represents the statistical difference between control and treated groups.