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. 2020 Jul 16;11:634. doi: 10.3389/fneur.2020.00634

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Copyright © 2020 Huang, Chen, Lin, Su and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Summary of the number of organs involved as irAEs in addition to irMG, treatment strategies, and mortality rate. X axis: treatments. Number of “+,” number of treatment(s) of pulsed immunosuppression (PE, IVIG, pulse methylprednisolone) applied. Y axis: number of organs involved as irAEs. Organs for statistic included skin, gut, endocrine, lung, muscle, cardiovascular, liver, hematologic, renal, nerve, and ophthalmologic system. Circle size: total case number. Circle gray scale color, mortality rate: black, 100% mortality; white, 0% mortality. Number above each circle: numerator, case number of irMG-related mortality; denominator, total case number of each treatment strategy. PE, plasma exchange; IVIG, intravenous immunoglobulin.