Table 2.

Multivariate regression analyses for hypoxanthine, xanthine, xanthine oxidoreductase activity and uric acid

	Regression coefficient	SE	Standardized regression coefficient (β)	t	P
Hypoxanthine
Age	−0.018	0.004	−0.175	−4.27	<0.001
Sex (male)	0.001	0.063	0.001	0.02	0.988
Use of antihyperuricemic drugs	−0.098	0.185	−0.021	−0.53	0.595
Body mass index	0.042	0.016	0.106	2.66	0.008
Smoking habit	0.250	0.088	0.118	2.83	0.005
log Xanthine	1.501	0.134	0.468	11.22	<0.001
R 2 = 0.307
log Xanthine
Age	0.003	0.001	0.105	2.90	0.004
Sex (Male)	0.017	0.018	0.034	0.92	0.357
Use of antihyperuricemic drugs	0.275	0.051	0.192	5.37	<0.001
log ALT	0.173	0.052	0.163	3.30	0.001
Hypoxanthine	0.141	0.011	0.456	12.59	<0.001
log XOR	0.130	0.029	0.215	4.51	<0.001
R 2 = 0.416
log XOR
Age	0.003	0.002	0.052	1.58	0.115
Sex (Male)	−0.003	0.028	−0.004	−0.11	0.912
Use of antihyperuricemic drugs	−0.219	0.081	−0.092	−2.69	0.007
log ALT	1.071	0.066	0.607	16.19	<0.001
log Triglycerides	0.179	0.052	0.119	3.41	0.001
log Xanthine	0.198	0.061	0.119	3.22	0.001
R 2 = 0.489
Uric acid
Age	−0.021	0.004	−0.243	−5.42	<0.001
Sex (Male)	0.505	0.050	0.396	10.09	<0.001
Use of antihyperuricemic drugs	−0.025	0.143	−0.007	−0.17	0.862
Body mass index	0.030	0.013	0.093	2.38	0.018
log ALT	0.498	0.118	0.176	4.21	<0.001
eGFR	−0.031	0.004	−0.352	−7.66	<0.001
log Triglycerides	0.277	0.094	0.115	2.94	0.003
R 2 = 0.358

ALT, alanine transaminase; eGFR, estimated glomerular filtration rate; SE, standard error; XOR, xanthine oxidoreductase.