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. 2020 Jul 24;133:154–161. doi: 10.1016/j.amjcard.2020.07.040

Table 3.

Predictors of inpatient mortality after multivariate regression using patient risk factors, inpatient complications as well as peak serum biomarkers levels

Variables Odds ratio (95% confidence interval) p-value
Age ≥ 65 (years) 3.9 (2.2–6.7) <0.001
Atrial fibrillation/flutter 2.5 (1.2–5.3) 0.014
Cerebrovascular disease 2.5 (1.3–5.0) 0.008
Peak D-dimer < 1 µg/ml Reference 0.013
Peak D-dimer ≥ 1 < 1.8 µg/ml 1.2 (0.4–3.7) 0.696
Peak D-dimer ≥ 1.8 < 4 µg/ml 2.7 (1.0–7.4) 0.049
Peak D-dimer ≥ 4 µg/ml 3.3 (1.2–9.0) 0.017
Peak high sensitivity troponin ≤ 18 ng/L Reference <0.001
Peak high sensitivity troponin 19–99 ng/L 3.0 (1.5–6.0) 0.002
Peak high sensitivity troponin ≥100 ng/L 7.7 (3.7–16.0) <0.001
Acute respiratory distress syndrome 14.6 (8.2–25.7) <0.001

Variables controlled for:

Risk factors: Age ≥ 65, Gender, Body Mass Index, Hypertension, Coronary Artery Disease, Heart Failure, Atrial Fibrillation/ Flutter, Cerebrovascular Disease, Immunosuppressed State, Chronic Obstructive Pulmonary Disease, Chronic Kidney Disease, Cirrhosis. Inpatient Clinical Data Elements: Peak levels of High Sensitivity Troponin, Lactate Dehydrogenase, C-Reactive Protein, Ferritin and D-dimer levels based on quartiles, Acute Respiratory Distress Syndrome, Acute Kidney Injury