Table 3.
Odds ratios (OR) or mean difference and 95% credible intervals (CrIs) of seven regimes with four endpoints.
| OR/MD (95%CrIs) | ||||||
|---|---|---|---|---|---|---|
| Overall clinical efficacy | ||||||
| GMD | 1.09 (0.15, 9.61) | 3.43 (0.37, 35.53) | 5.37 (0.35, 113.24) | 3.29 (0.55, 21.69) | 3.27 (0.28, 41.96) | 1.38 (0.19, 10.36) |
| 0.91 (0.10, 6.75) | PPIs + GMD | 3.06 (0.60, 15.96) | 4.71 (0.46, 72.18) | 2.99 (1.09, 8.60) | 2.95 (0.39, 24.96) | 1.26 (0.36, 4.54) |
| 0.29 (0.03, 2.67) | 0.33 (0.06, 1.68) | Jianpi therapy | 1.49 (0.17, 19.80) | 0.98 (0.25, 3.25) | 1.00 (0.14, 5.88) | 0.42 (0.14, 1.12) |
| 0.19 (0.01, 2.87) | 0.21 (0.01, 2.17) | 0.67 (0.05, 5.99) | Jianpi therapy + PPIs | 0.65 (0.05, 5.23) | 0.63 (0.04, 7.79) | 0.28 (0.02, 1.85) |
| 0.30 (0.05, 1.82) | 0.33 (0.12, 0.92) | 1.02 (0.31, 3.98) | 1.54 (0.19, 19.54) | Ligan Hewei therapy | 1.00 (0.18, 5.67) | 0.42 (0.19, 0.86) |
| 0.31 (0.02, 3.51) | 0.34 (0.04, 2.59) | 1.00 (0.17, 7.36) | 1.59 (0.13, 27.40) | 1.00 (0.18, 5.62) | Ligan Hewei therapy + PPIs | 0.43 (0.09, 1.92) |
| 0.73 (0.10, 5.14) | 0.79 (0.22, 2.79) | 2.40 (0.90, 7.38) | 3.60 (0.54, 40.86) | 2.36 (1.16, 5.24) | 2.35 (0.52, 11.22) | PPIs |
| Efficacy under gastroscope | ||||||
| GMD | 1.65 (0.10, 26.24) | 11.61 (0.25, 568.68) | 51.90 (0.92, 3257.59) | 7.11 (0.74, 68.82) | 26.28 (0.58, 1280.91) | 7.98 (0.31, 175.41) |
| 0.61 (0.04, 9.72) | PPIs + GMD | 6.89 (0.21, 254.10) | 31.25 (0.78, 1584.93) | 4.25 (0.88, 22.93) | 16.30 (0.54, 600.63) | 4.83 (0.33, 75.59) |
| 0.09 (0.00, 3.99) | 0.15 (0.00, 4.80) | Jianpi therapy | 4.24 (0.18, 128.60) | 0.61 (0.03, 13.90) | 2.29 (0.11, 48.17) | 0.69 (0.07, 5.85) |
| 0.02 (0.00, 1.09) | 0.03 (0.00, 1.27) | 0.24 (0.01, 5.64) | Jianpi therapy + PPIs | 0.14 (0.00, 3.71) | 0.55 (0.02, 14.63) | 0.17 (0.01, 1.87) |
| 0.14 (0.01, 1.35) | 0.24 (0.04, 1.14) | 1.64 (0.07, 37.39) | 7.19 (0.27, 247.10) | Ligan Hewei therapy | 3.73 (0.18, 87.69) | 1.15 (0.12, 10.03) |
| 0.04 (0.00, 1.72) | 0.06 (0.00, 1.85) | 0.44 (0.02, 8.98) | 1.83 (0.07, 56.23) | 0.27 (0.01, 5.44) | Ligan Hewei therapy + PPIs | 0.30 (0.03, 2.61) |
| 0.13 (0.01, 3.18) | 0.21 (0.01, 3.07) | 1.44 (0.17, 13.42) | 6.06 (0.53, 99.03) | 0.87 (0.10, 8.10) | 3.37 (0.38, 30.87) | PPIs |
| Improvement of acid regurgitation | ||||||
| PPIs + GMD | -1.25 (-3.49, 0.92) | -0.18 (-1.13, 0.71) | 0.26 (-1.81, 2.18) | -0.31 (-1.93, 1.21) | ||
| 1.25 (-0.92, 3.49) | Jianpi therapy | 1.07 (-0.93, 3.10) | 1.51 (-0.48, 3.45) | 0.93 (-0.56, 2.47) | ||
| 0.18 (-0.71, 1.13) | -1.07 (-3.10, 0.93) | Ligan Hewei therapy | 0.44 (-1.40, 2.19) | -0.13 (-1.46, 1.13) | ||
| -0.26 (-2.18, 1.81) | -1.51 (-3.45, 0.48) | -0.44 (-2.19, 1.40) | Ligan Hewei therapy + PPIs | -0.58 (-1.84, 0.74) | ||
| 0.31 (-1.21, 1.93) | -0.93 (-2.47, 0.56) | 0.13 (-1.13, 1.46) | 0.58 (-0.74, 1.84) | PPIs | ||
| Improvement of heartburn | ||||||
| PPIs + GMD | -0.15 (-0.84, 0.52) | 0.41 (-1.16, 1.92) | -0.34 (-1.56, 0.85) | |||
| 0.15 (-0.52, 0.84) | Ligan Hewei therapy | 0.56 (-0.83, 1.91) | -0.19 (-1.18, 0.78) | |||
| -0.41 (-1.92, 1.16) | -0.56 (-1.91, 0.83) | Ligan Hewei therapy + PPIs | -0.76 (-1.73, 0.24) | |||
| 0.34 (-0.85, 1.56) | 0.19 (-0.78, 1.18) | 0.76 (-0.24, 1.73) | PPIs | |||
OR or MD and 95%CrIs below the treatments should be read from row to column while those above should be read from column to row. PPIs, proton pump inhibitors; GMD, gastrointestinal motility drugs.
Bolded data indicated P < 0.05.