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Silencing E2F1 inhibits BC cell cycle and proliferation. (a) GSEA enrichment analysis of E2F1. (b) The mRNA expression of E2F1 in BC cells was tested by qRT-PCR. (c–f) Effects of silencing E2F1 on cell (c) proliferation, (d) growth, (e) apoptosis, and (f) cell cycle were detected by MTT, colony formation assay, and flow cytometry. Each result was a representative of 3 experiments, ∗p < 0.05.
