Table 2.
Regression equations and correlation coefficients for 11 Gelsemium alkaloids in rat plasma.
| Compound | Linear range (ng/mL) | Regression equation | Correlation coefficient |
|---|---|---|---|
| Humantenirine | 0.1-200 | y = 0.0125x − 0.0041 | 0.9962 |
| Humantenine | 0.1-200 | y = 0.0092x − 0.0053 | 0.9991 |
| Akuammidine | 0.1-200 | y = 0.0058x + 0.0134 | 0.9992 |
| Gelsevirine | 0.1-200 | y = 0.0136x − 0.0060 | 0.9995 |
| Rankinidine | 0.1-200 | y = 0.0117x + 0.0067 | 0.9987 |
| n-Methoxyanhydrovobasinediol | 0.1-200 | y = 0.0153x + 0.0125 | 0.9993 |
| Gelsenicine | 0.1-200 | y = 0.0161 x + 0.0010 | 0.9985 |
| Gelsemine | 0.1-200 | y = 0.0018x − 0.0013 | 0.9967 |
| Koumine | 0.1-200 | y = 0.0043x − 0.0014 | 0.9980 |
| Koumidine | 0.1-200 | y = 0.0035x + 0.0025 | 0.9998 |
| Sempervirine | 0.1-200 | y = 0.0048x + 0.0028 | 0.9950 |
y = peak area ratio of Gelsemium alkaloids versus IS; x = concentration of Gelsemium alkaloids.