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. 2020 Jul 14;2020:1293935. doi: 10.1155/2020/1293935

Figure 6.

Figure 6

SDG could not extend the long-lived C. elegans mutants from genes involved in energy processing. (a) The pharyngeal pumping of wild-type C. elegans (N2) treated with or without 500 μM of SDG. The pharyngeal pumping of C. elegans was significantly reduced by SDG (p < 0.0001, two-tailed t-test). (b) The mean lifespan of eat-2 mutant strain DA1116 treated with or without 500 μM of SDG at 20°C. (c) The mean lifespan of aak-2 mutant strain RB754 treated with or without 500 μM of SDG at 20°C. (d) The mean lifespan of isp-1 mutant strain MQ887 treated with or without 500 μM of SDG at 20°C. SDG could not further extend the mean lifespan of these mutants expect for the isp-1 mutant strain MQ887. A statistically significant p value was calculated by the t-test or log-rank test; ★★★p < 0.0001. The results from three repeated experiments and the statistical details are summarized in supplementary Tables S5 and S13.