Table 2.
Measured concentrations of metabolites in control and multiple sclerosis groups and Mann–Whitney U test comparison for median.
Metabolites | Control group | MS group | M.-W. U test P value | ||||
---|---|---|---|---|---|---|---|
Median conc. (μmol/ml) | Mean conc. (μmol/ml) | s.d. | Median conc. (μmol/ml) | Mean conc. (μmol/ml) | s.d. | ||
Asp | 15.0507 | 15.6657 | 5.2672 | 32.1554 | 30.6449 | 15.8740 | 0.0097 |
C8:1-carnitine | 0.0472 | 0.0494 | 0.0121 | 0.0393 | 0.0407 | 0.0076 | 0.0530 |
C5OH-carnitine | 0.0125 | 0.0125 | 0.0025 | 0.0141 | 0.0154 | 0.0066 | 0.0993 |
Glu | 63.2383 | 62.1980 | 12.4526 | 80.8461 | 89.0735 | 41.6262 | 0.1457 |
C5-carnitine | 0.0391 | 0.0499 | 0.0353 | 0.0337 | 0.0372 | 0.0226 | 0.1736 |
Tyr | 44.6430 | 53.7064 | 25.8724 | 37.7501 | 41.5309 | 12.5512 | 0.1736 |
Val | 78.0683 | 84.5595 | 30.3860 | 68.6876 | 74.3788 | 18.9949 | 0.2053 |
C3-carnitine | 0.1186 | 0.1470 | 0.0707 | 0.1117 | 0.1166 | 0.0658 | 0.2226 |
Cit | 18.9037 | 18.3220 | 4.0953 | 16.2658 | 16.6069 | 3.5469 | 0.2601 |
C8-carnitine | 0.0251 | 0.0404 | 0.0346 | 0.0433 | 0.0416 | 0.0157 | 0.2750 |
Arg | 45.6852 | 45.5796 | 9.9030 | 40.7909 | 41.8867 | 13.8405 | 0.3015 |
Pro | 136.2588 | 160.0983 | 66.9696 | 117.1770 | 138.5637 | 66.4677 | 0.3470 |
C3DC-carnitine | 0.0462 | 0.0449 | 0.0104 | 0.0484 | 0.0498 | 0.0102 | 0.3713 |
Met | 4.2999 | 5.0050 | 1.9571 | 3.7745 | 4.7199 | 1.9774 | 0.4228 |
Phe | 27.6062 | 28.6280 | 8.4151 | 22.7213 | 26.5824 | 9.0137 | 0.4228 |
Leu+Ile | 75.4267 | 82.0059 | 30.8033 | 70.1791 | 75.0415 | 21.4271 | 0.5070 |
Orn | 38.8374 | 39.2365 | 6.9759 | 35.1740 | 38.7100 | 14.2728 | 0.5369 |
C18:1-carnitine | 0.1713 | 0.1752 | 0.0713 | 0.1843 | 0.1804 | 0.0523 | 0.5369 |
C10:1-carnitine | 0.0498 | 0.0710 | 0.0446 | 0.0646 | 0.0610 | 0.0320 | 0.6642 |
Ala | 122.9021 | 113.9486 | 35.2646 | 118.6330 | 124.2386 | 64.5191 | 0.8017 |
C2-carnitine | 1.9548 | 2.3722 | 0.8908 | 2.2165 | 2.3927 | 0.8565 | 0.8017 |
C10-carnitine | 0.0442 | 0.0669 | 0.0535 | 0.0543 | 0.0509 | 0.0248 | 0.8017 |
C4OH-carnitine | 0.0128 | 0.0130 | 0.0057 | 0.0127 | 0.0127 | 0.0047 | 0.8344 |
Carnitine | 15.0021 | 15.3318 | 4.0812 | 14.1629 | 15.7528 | 7.6604 | 0.8372 |
C4-carnitine | 0.0572 | 0.1013 | 0.0848 | 0.0634 | 0.0694 | 0.0274 | 0.8731 |
C14:1-carnitine | 0.0165 | 0.0183 | 0.0103 | 0.0176 | 0.0176 | 0.0058 | 0.9445 |
Gly | 98.6914 | 103.7987 | 30.5344 | 101.8677 | 104.9996 | 30.7912 | 0.9454 |
C6-carnitine | 0.0163 | 0.0278 | 0.0229 | 0.0208 | 0.0208 | 0.0076 | 0.9815 |
s.d.: standard deviation.