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. 2020 Jun 14;16(13):2308–2322. doi: 10.7150/ijbs.44774

Figure 1.

Figure 1

Schematic overview of BA receptors. The available crystal structures of BA receptors are FXR, PXR, VDR, CAR, CHMR2 are shown in 3D and in cartoon representation. The homology models of TGR5 and FATP5 were developed in the absence of their crystal structure. All the BA receptors are summarized in the Figure. The 2D structures of the available modulators of BAs receptors are shown (the small molecule which is reported against metabolic disorder are only picked). NF is not found.