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. 2020 Jul 7;16(13):2477–2478. doi: 10.7150/ijbs.49125

Figure 1.

Figure 1

Identification of glucocorticoids as effective drugs for COVID-19 patients. Through bioinformatics-based screening for ACE2 agonists, a group of glucocorticoids were found to increase ACE2 expression and inhibit IL-6 production. Treatment of severe or critical COVID-19 patients revealed significant improvement in clinical parameters. Modified from figures provided by Dr. Yingyan Yu.