Table 1.
Correlation between LINC01123 expression and clinicopathologic characteristics in hepatocellular carcinoma
| Characteristics | n=80 | LINC01123 | P (chi-square test) | ||
|---|---|---|---|---|---|
| Low expression (n=40) | High expression (n=40) | ||||
| Age (years) | <50 | 35 | 17 | 18 | 0.822 |
| ≥50 | 45 | 23 | 22 | ||
| Sex | Male | 63 | 34 | 29 | 0.172 |
| Female | 17 | 6 | 11 | ||
| HBV | No | 28 | 16 | 12 | 0.348 |
| Yes | 52 | 24 | 28 | ||
| Serum AFP level (ng/mL) | <20 | 27 | 15 | 12 | 0.478 |
| ≥20 | 53 | 25 | 28 | ||
| Tumor size (cm) | <5 | 26 | 19 | 7 | 0.004* |
| ≥5 | 54 | 21 | 33 | ||
| No. of tumor nodules | 1 | 65 | 35 | 30 | 0.152 |
| ≥2 | 15 | 5 | 10 | ||
| Cirrhosis | No | 35 | 19 | 16 | 0.499 |
| Yes | 45 | 21 | 24 | ||
| Venous infiltration | No | 44 | 27 | 17 | 0.025* |
| Yes | 36 | 13 | 23 | ||
| Edmondson-Steiner grade | I+II | 57 | 32 | 25 | 0.084 |
| III+IV | 23 | 8 | 15 | ||
| TNM stage | I+II | 63 | 37 | 26 | 0.003* |
| III+IV | 17 | 3 | 14 | ||
HBV, hepatitis B virus; AFP, alpha-fetoprotein; TNM, tumor-node-metastasis.
The “low” or “high” expression of LINC01123 level was defined according to the cut-off value, which was defined as the median value of the cohort of patients tested. *Statistically significant.