Table 3.
Echocardiographic and electrocardiographic measurements before percutaneous atrial septal defect closure in adults (baseline) and 1 year after ASD closure.
|
Baseline (prior to ASD closure) |
1 year post ASD closure |
p-value |
|||
|---|---|---|---|---|---|
| Complete cases, n(%) | Mean ± SD or median [IQR] | Complete cases, n(%)# | Mean ± SD or median [IQR] | ||
| Clinical characteristics | |||||
| NYHA class | 50 (100) | 42 (86) | 0.020 | ||
| class I | 34 (68) | 34 (81) | |||
| class II | 16 (32) | 8 (19) | |||
| Electrocardiography | |||||
| PR-interval* | 41 (100) | 171 ± 28 | 30 (75) | 159 ± 31 | 0.001 |
| QRS duration | 49 (98) | 112 ± 22 | 38 (78) | 109 ± 21 | 0.110 |
| Echocardiography | |||||
| LV end-diastolic dimension, mm | 50 (100) | 46.7 ± 6.3 | 41 (84) | 49.1 ± 4.9 | 0.009 |
| E/E' | 35 (70) | 8.3 [6.7–9.2] | 31 (63) | 8.5 [7.3–10.4] | 0.808 |
| E/A | 35 (70) | 1.1 [1.0–1.4] | 33 (67) | 1.05 [0.8–1.5] | 0.683 |
| Left atrial dimension, mm | 49 (98) | 40.4 ± 9.6 | 40 (82) | 38.3 ± 10.6 | 0.084 |
| Right atrial area, cm2 | 49 (98) | 23.3 [18.7–28.4] | 40 (82) | 18.0 [14.5–22.5] | <0.001 |
| RVED area, cm2 | 49 (98) | 34.9 ± 8.5 | 40 (82) | 28.2 ± 7.5 | <0.001 |
| RVED basal diameter, mm | 50 (100) | 49.5 ± 6.8 | 42 (86) | 44.0 ± 6.8 | <0.001 |
| RVED apex to base length, mm | 49 (98) | 85.6 ± 9.2 | 40 (82) | 82.1 ± 9.3 | 0.001 |
| RV fractional area change, % | 49 (98) | 41.0 ± 9.5 | 40 (82) | 37.7 ± 7.8 | 0.155 |
| TAPSE, mm | 46 (92) | 27.8 ± 5.7 | 29 (59) | 23.2 ± 3.6 | <0.001 |
| Right atrial pressure | 44 (88) | 35 (71) | 0.096 | ||
| Range 0–5 mmHg | 36 (72) | 32 (91) | |||
| Range 5–10 mmHg | 8 (16) | 6 (9) | |||
| RV systolic pressure, mmHg | 39 (78) | 28 [26–38] | 29 (59) | 27 [23–36 (4] | 0.024 |
Table legend:#One patient was excluded from the 1-year analysis because of cardiac device erosion. *Atrial fibrillation, atrial flutter or pacemaker rhythm are not included.
Abbreviations: ASD = atrial septal defect, NYHA = New York Heart Association, LV = left ventricular, RVED = right ventricular end-diastolic, TAPSE = tricuspid annular plane systolic excursion, RV = right ventricular.