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Persistence of CD28- and 4-1BB-Based CAR-T Cells after Infusion for Different Time Intervals
(A and B) Variation trends of engrafted CD28 (A) and 4-1BB CAR-T cells (B) over different time periods determined by flow cytometry analysis of CAR-T cells in peripheral blood. (C) Peak numbers of CD28- and 4-1BB-based CAR-T cells. ∗∗p < 0.01, and the error bars represent the standard derivation.
