TABLE 3.
Groups | MT | LD | MT/LD (%) |
agomir NC | 70.05 ± 10.02 | 2.91 ± 0.56 | 24.69 ± 5.41 |
miR-9 agomir | 34.91 ± 2.79* | 7.13 ± 0.28* | 4.90 ± 0.43* |
miR-9 agomir + oe-SDC2 | 68.26 ± 9.62 | 3.12 ± 0.25 | 23.76 ± 4.45 |
miR-9, microRNA-9; VR, vascular remodeling; MT, medium wall thickness; LD, lumen diameter; MT/LD, medium wall thickness/lumen diameter; NC, negative control; *p < 0.05 vs. mice treated with agomir NC; n = 8 for mice upon each treatment; All data were measurement data and expressed as mean ± standard deviation. Comparisons were analyzed using the unpaired t-test. The experiment was repeated 3 times.