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. 2020 Jul 16;7:43. doi: 10.3389/fsurg.2020.00043

Table 3.

Studies related to thyroid cancer stem cells published from 2008 to 2019 (as per HDAS search on 19 July 2019).

Publication title References Models used
In vitro identification and characterization of CD133(pos) cancer stem-like cells in anaplastic thyroid carcinoma cell lines (173) 2D
Medullary Thyroid Carcinoma Cell Lines Contain a Self-Renewing CD133 Population that Is Dependent on Ret Proto-Oncogene Activity (174) 2D and spheroids
Tumorigenic and Metastatic Activity of Human Thyroid Cancer Stem Cells (175) 2D, spheroid and PDX
Doxorubicin fails to eradicate cancer stem cells derived from anaplastic thyroid carcinoma cells: characterization of resistant cells (176) 2D and spheroids
Insulin receptor isoforms and insulin-like growth factor receptor in human follicular cell precursors from papillary thyroid cancer and normal thyroid (177) 2D and spheroids
Phenotypic Characterization of Metastatic Anaplastic Thyroid Cancer Stem Cells (168) 2D, spheroid and PDX
Detection of Thyroid Cancer Stem Cells in Papillary Thyroid Carcinoma (53) 2D, spheroid and PDX
SNAIL induces epithelial-to-mesenchymal transition and cancer stem cell-like properties in aldehyde dehydroghenase-negative thyroid cancer cells (178) 2D, spheroid and PDX
Analysis of multiple markers for cancer stem-like cells in human thyroid carcinoma cell lines (179) 2D and spheroids
Stemness in Human Thyroid Cancers and Derived Cell Lines: The Role of Asymmetrically Dividing Cancer Stem Cells Resistant to Chemotherapy (180) 2D and PDX
Thyrospheres From Normal or Malignant Thyroid Tissue Have Different Biological, Functional, and Genetic Features (181) Spheroids
Molecular profiles of cancer stem-like cell populations in aggressive thyroid cancers (182) 2D and spheroids
Resistance of papillary thyroid cancer stem cells to chemotherapy (169) Spheroids
Generation of Novel Thyroid Cancer Stem-Like Cell Clones (170) 2D, spheroid and PDX
Intracellular redox status controls spherogenicity, an in vitro cancer stem cell marker, in thyroid cancer cell lines (183) 2D and spheroids
Thyroid Cancer Stem-Like Cell Exosomes: Regulation of EMT via Transfer of LncRNAs (184) 2D and spheroids
β-catenin nuclear translocation represses thyroid cancer stem cells differentiating into cells with sodium-iodine symporter functional expression (185) 2D and PDX
Effect of low-dose tungsten on human thyroid stem/precursor cells and their progeny (186) 2D and spheroid