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(A) Use of antibodies against cell surface proteins present on exosomes allows for isolation of neuronal-, microglial-, and astrocyte-derived exosomes. (B) The accumulation of intraluminal vesicles (ILVs), exosome precursors, forms Multivesicular bodies (MVBs). MVBs fuse with the plasma membrane, releasing exosomes to the extracellular environment. Created with Biorender.com.
