TABLE 2.

Cardiac parameters pre-bedrest and at end-best with and without −30 mm Hg lower body negative pressure (LBNP).

		Control		RVE		NeX		3-way ANOVA (p)
Variable	LBNP Level	Pre-HDBR	End-HDBR	Pre-HDBR	End-HDBR	Pre-HDBR	End-HDBR	BR	CM	Position (LBNP)	BR*CM	BR*Position
LVM (g)	0 mm Hg	155 ± 52	132 ± 17	149 ± 57	145 ± 54	154 ± 53	148 ± 49	0.1	0.36		0.6
LVEDV (ml)	0 mm Hg	158 ± 53	134 ± 31	171 ± 48	143 ± 40	163 ± 51	139 ± 39	0.0003	0.32	0.088	0.26	0.21
	−30 mm Hg	129 ± 39	97 ± 21	129 ± 34	98 ± 22	129 ± 35	105 ± 29
LVESV (ml)	0 mm Hg	58 ± 26	46 ± 13	59 ± 24	47 ± 16	57 ± 23	48 ± 20	0.0009	0.91	0.008	0.63	0.46
	−30 mm Hg	49 ± 23	32 ± 14	50 ± 19	35 ± 15	48 ± 16	40 ± 17
SV (ml)	0 mm Hg	99 ± 29	88 ± 20	112 ± 26	95 ± 25	106 ± 29	91 ± 20	0.0007	0.51	0.045	0.27	0.57
	−30 mm Hg	80 ± 18	65 ± 9	78 ± 15	63 ± 8	81 ± 20	65 ± 15
Ejection	0 mm Hg	0.64 ± 0.06	0.66 ± 0.04	0.66 ± 0.05	0.67 ± 0.03	0.66 ± 0.04	0.67 ± 0.06	0.32	0.97	0.32	0.27	0.63
Fraction	−30 mm Hg	0.64 ± 0.08	0.66 ± 0.04	0.66 ± 0.05	0.67 ± 0.03	0.66 ± 0.04	0.67 ± 0.06
Cardiac Output	0 mm Hg	5.28 ± 1.2	4.97 ± 0.51	6.16 ± 1.65	5.16 ± 1.18	5.64 ± 0.68	5.1 ± 0.81	0.033	0.23	0.005	0.32	0.18
(L/min)	−30 mm Hg	4.77 ± 0.79	4.54 ± 0.46	4.86 ± 0.92	4.59 ± 0.65	4.97 ± 0.61	4.6 ± 0.67
GCS (%)	0 mm Hg	−20.91 ± 3.58	−22.74 ± 2.53	−22.82 ± 3.67	−22.78 ± 2.48	−21.88 ± 2.72	−22.95 ± 3.31	0.34	0.85	0.06	0.41	0.21
	−30 mm Hg	−20.49 ± 3.31	−21.7 ± 3.14	−21.28 ± 3.07	−21.06 ± 3.55	−20.64 ± 2.9	−20.76 ± 3.82
GCSR-E (1/s)	0 mm Hg	1.19 ± 0.36	1.2 ± 0.19	1.31 ± 0.3	1.23 ± 0.23	1.31 ± 0.31	1.28 ± 0.19	0.63	0.038	0.11	0.92	0.02
	−30 mm Hg	1.2 ± 0.27	1.46 ± 0.27	1.3 ± 0.21	1.5 ± 0.39	1.31 ± 0.27	1.48 ± 0.28

LVM, left ventricular mass; LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; SV, stroke volume; GCS, global circumferential strain; GCSR-E, early diastolic circumferential strain rate. Significant differences are bolded.