TABLE 5.

Within-group and between-groups comparison of results on pre- and post-treatment primary outcome measures.

	ACE-t participants			ACE-nt participants			Group comparison
Domain	Median (25th–75th percentile)		Wilcoxon	Median (25th–75th percentile)		Wilcoxon	Mann–Whitney U
Test, subscales	Pre-treatment	Post-treatment	p	Pre-treatment	Post-treatment	p	p
General cognition
ADAS-COG	28.00 (25.00–36.00)	22.50 (18.00–26.00)	0.002	21.80 (17.60–24.00)	21.00 (17.30–26.00)	0.625	**
Behavioral
NPI
Frequency	10.33 (7.00–11.00)	1.50 (1.00–5.00)	0.084	17.00 (6.00–23.00)	23.50 (14.00–27.00)	0.275	*
Distress	5.83 (4.00–8.00)	1.00 (0.00–2.00)	0.084	7.00 (4.00–12.00)	8.00 (5.00–14.00)	0.547	**
Quality of life
QOL
PWAD	31.25 (27.00–36.00)	35.33 (31.00–37.00)	0.027	32.50 (26.00–36.00)	32.44 (28.00–38.00)	1.00	-
CG	31.00 (29.00–33.00)	31.50 (26.00–37.00)	0.232	30.50 (28.00–34.00)	29.50 (26.00–31.00)	0.734	-

ADAS-Cog, Alzheimer’s Disease Assessment Scale; ACE-t, people treated with “Art, Colors, and Emotions” treatment; ACE-nt, people with the usual care program; NPI, Neuropsychiatric Inventory Scale; QOL, quality of life; PWAD, people with Alzheimer’s disease; CG, caregiver. Statistically significant p values (p < 0.05) are reported in italics. *p ≤ 0.05; **p ≤ 0.01.