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. 2020 Jul 23;11(7):559. doi: 10.1038/s41419-020-02766-6

Fig. 4. MiR-628-5p directly binds to the 3′UTR of PIN1 mRNA.

Fig. 4

a The potential binding sites of miR-6285p in the PIN1 mRNA 3′UTR. b, c The mRNA abundance of PIN1 mRNA in AGO2 immunoprecipitates that from SGC-7901-transfected miR-628-5p mimic, inhibitor, or their negative control. d The sequence of the WT or mutant PIN1 3′UTR reporter plasmid. e, f The relative luciferase activity in SGC-7901 that transfected miR-628-5p mimic, inhibitor, or their corresponding negative control that cotransfected with WT or mutant PIN1 3′UTR reporter plasmid. The data are shown as the mean ± s.d. (n = 3) in cell lines. *p < 0.05, **p < 0.01, ***p < 0.001, ns, no significance.