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SOCS1 knockdown promotes PGE2 secretion by MSCs. MSC/CTLsh or MSC/SOCS1sh were stimulated with different doses (0, 0.5 and 5 ng/ml) of TNF-α/IFN-γ for 12 h and then the level of PGE2 in the culture medium was measured by ELISA. Data were representative of three independent experiments. **p<0.01. Note: CTLsh, MSC/CTLsh; SOCS1sh, MSC/SOCS1sh.
