Table 3.
Spearman rank correlations of saliva Lf levels with MMSE and CDR in the whole dataset and diagnostic groups.
Cohort 1 | ||||||||
---|---|---|---|---|---|---|---|---|
Correlation coefficient | ||||||||
Whole dataset | Control | MCI/AD | FTD | |||||
MMSE | 0•42a | 0•04 | −0•03 | 0•69b | ||||
CDR | −0•49a | – | −0•19 | −0•59b | ||||
Cohort 2 | ||||||||
Correlation coefficient | ||||||||
Whole dataset | Control | MCI-PET+ | MCI-PET− | |||||
MMSE | 0•40a | 0•20 | −0•27 | −0•04 | ||||
CDR | −0•53a | – | – | – |
Abbreviations: MCI, mild cognitive impairment; AD, Alzheimer's disease dementia; FTD, frontotemporal dementia; PET+, positive amyloid PET scan; PET-, negative amyloid PET scan; MMSE, Mini-Mental State Examination; CDR, Clinical Dementia Rating.
[Spearman:
p < 0•0001.
p < 0•01].