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. 2020 Jul 16;11:1381. doi: 10.3389/fimmu.2020.01381

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Copyright © 2020 Qiu, Liu, Liang, Nie and Dai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Figure 3A — Emodin suppresses the expansion of effector CD8⁺ T cells. (A) Draining lymph node (LN) and spleen cells from emodin- and CsA-treated B6 mice transplanted with BALB/c skin were isolated 10 days after transplantation and analyzed via FACS analysis. Column graphs show the percentages of CD8⁺CD44^highCD62L^low effector T cells (Teff) from LNs and spleens. Data are presented as means ± SD from two separate experiments (*P < 0.05, **P < 0.01, n = 4 mice/group).