Table 5. Changes in clinical laboratory parameters from baseline to week 16 (full analysis set).

Variable	Baseline (wk 0) (n=35)	Wk 16 (n=35)	Δ, Mean (95% CI)	p value
Glucose (mg/dL)	117.1±24.7	126.6±34.3	9.5 (1.5, 17.4)	0.020*
HbA1c (%)	6.6±0.7	6.8±1.1	0.1 (−0.1, 0.3)	0.303*
Creatinine (mg/dL)	0.8±0.1	0.8±0.2	0.0 (−0.0, 0.0)	0.162*
Total bilirubin (mg/dL)	0.6±0.2	0.7±0.3	0.0 (0.0, 0.1)	0.050*
AST (IU/L)	23.8±8.5	26.0±8.9	2.2 (0.4, 4.1)	0.016*
ALT (IU/L)	22.5±11.6	26.8±14.8	4.2 (1.3, 7.2)	0.005*
Creatine kinase (IU/L)	90.2±47.8	97.2±52.6	9.5 (−2.3, 21.4)	0.367†

Data are expressed as mean±standard deviation.

^*Paired t-test; ^†Wilcoxon's signed-rank test.

HbA1c, hemoglobin A1c; CI, confidence interval; AST, aspartate aminotransferase; ALT, alanine aminotransferase.